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Regulation of polo-like kinase 1 by DNA damage and PP2A/B55α

In addition to governing mitotic progression, Plk1 also suppresses the activation of the G2 DNA damage checkpoint and promotes checkpoint recovery. Previous studies have shown that checkpoint activation after DNA damage requires inhibition of Plk1, but the underlying mechanism of Plk1 regulation was...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Wang, Ling, Guo, Qingyuan, Fisher, Laura A, Liu, Dongxu, Peng, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615057/
https://ncbi.nlm.nih.gov/pubmed/25483054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.986392
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