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Resistance to targeted cancer drugs through hepatocyte growth factor signaling

Cancer therapeutics that target a signaling pathway to which the cancer cells are addicted can deliver dramatic initial responses, but resistance is nearly always inevitable. A variety of mechanisms that cancer cells employ to escape from targeted cancer drugs have been described. We review here the...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Heynen, Guus JJE, Fonfara, Aldona, Bernards, René
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615055/
https://ncbi.nlm.nih.gov/pubmed/25426675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.988033
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