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A dynein independent role of Tctex-1 at the kinetochore

Dynein light chains are accessory subunits of the cytoplasmic dynein complex, a minus-end directed microtubule motor. Here, we demonstrate that the dynein light chain Tctex-1 associates with unattached kinetochores and is essential for accurate chromosome segregation. Tctex-1 knockdown in cells does...

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Pubblicato in:Cell Cycle
Autori principali: Liu, Chenshu, Chuang, Jen-Zen, Sung, Ching-Hwa, Mao, Yinghui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614829/
https://ncbi.nlm.nih.gov/pubmed/25928583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.1000217
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