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A dynein independent role of Tctex-1 at the kinetochore
Dynein light chains are accessory subunits of the cytoplasmic dynein complex, a minus-end directed microtubule motor. Here, we demonstrate that the dynein light chain Tctex-1 associates with unattached kinetochores and is essential for accurate chromosome segregation. Tctex-1 knockdown in cells does...
Shranjeno v:
| izdano v: | Cell Cycle |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614829/ https://ncbi.nlm.nih.gov/pubmed/25928583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.1000217 |
| Oznake: |
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