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Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.

Pharmacologic effects in brain caused by systemic administration of neuropeptides are prevented by poor transport of the peptide through the brain vascular endothelium, which comprises the blood-brain barrier in vivo. In the present study, successful application of a chimeric peptide approach to enh...

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Detalhes bibliográficos
Main Authors: Bickel, U, Yoshikawa, T, Landaw, E M, Faull, K F, Pardridge, W M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46146/
https://ncbi.nlm.nih.gov/pubmed/8385339
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