Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury

Our objective was to identify microRNA (miRNA) biomarkers of drug-induced liver and kidney injury by profiling the circulating miRNome in patients with acetaminophen overdose. Plasma miRNAs were quantified in age- and sex-matched overdose patients with (N = 27) and without (N = 27) organ injury (APA...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Vliegenthart, A. D. B., Shaffer, J. M., Clarke, J. I., Peeters, L. E. J., Caporali, A., Bateman, D. N., Wood, D. M., Dargan, P. I., Craig, D. G., Moore, J. K., Thompson, A. I., Henderson, N. C., Webb, D. J., Sharkey, J., Antoine, D. J., Park, B. K., Bailey, M. A., Lader, E., Simpson, K. J., Dear, J. W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614545/
https://ncbi.nlm.nih.gov/pubmed/26489516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15501
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