Destabilization of pluripotency in the absence of Mad2l2

The induction and maintenance of pluripotency requires the expression of several core factors at appropriate levels (Oct4, Sox2, Klf4, Prdm14). A subset of these proteins (Oct4, Sox2, Prdm14) also plays crucial roles for the establishment of primordial germ cells (PGCs). Here we demonstrate that the...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Pirouz, Mehdi, Rahjouei, Ali, Shamsi, Farnaz, Eckermann, Kolja Neil, Salinas-Riester, Gabriela, Pommerenke, Claudia, Kessel, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614513/
https://ncbi.nlm.nih.gov/pubmed/25928475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026485
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