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Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex
Cyclin-dependent kinase 5 (Cdk5) is a unique member of a family of serine/threonine cyclin-dependent protein kinases. We previously demonstrated disruption of Cdk5 gene expression in mice impairs T-cell function and ameliorates T-cell-mediated neuroinflammation. Here, we show Cdk5 modulates gene exp...
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| Veröffentlicht in: | Cell Cycle |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614394/ https://ncbi.nlm.nih.gov/pubmed/25785643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.987621 |
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