FLJ25439, a novel cytokinesis-associated protein, induces tetraploidization and maintains chromosomal stability via enhancing expression of endoplasmic reticulum stress chaperones

Investigation of the mechanisms leading to aneuploidy and polyploidy is critical to cancer research. Previous studies have provided strong evidence of the importance of tetraploidization as an early step in tumorigenesis. In cancer cells, tetraploid cells may contribute to abnormal mitotic progressi...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Pan, Tai-Long, Hsu, Shu-Yuan, Wang, Pei-Wen, Cheng, Ya-Ting, Chang, Yu-Chen, Saha, Sudipta, Hu, Jiwei, Ouyang, Pin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614365/
https://ncbi.nlm.nih.gov/pubmed/25751302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1010906
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