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Selective inhibition of dopamine‐beta‐hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex

INTRODUCTION: Disulfiram has been claimed to be useful in cocaine addiction therapy, its efficacy being attributed to dopamine‐beta‐hydroxylase (DBH) inhibition. Our previous results indicate that disulfiram and the selective DBH inhibitor nepicastat increase extracellular dopamine (DA) in the rat m...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Devoto, Paola, Flore, Giovanna, Saba, Pierluigi, Frau, Roberto, Gessa, Gian L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614051/
https://ncbi.nlm.nih.gov/pubmed/26516613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.393
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