Hepoxilin A3 is the endogenous lipid mediator opposing hypotonic swelling of intact human platelets.

When human blood platelets are exposed to hypotonic medium they swell first but, shortly thereafter, revert toward their original volume in a process termed regulatory volume decrease (RVD). RVD is the result of an enhanced efflux of K+ and Cl- ions and associated water. Platelet RVD is controlled b...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Margalit, A, Sofer, Y, Grossman, S, Reynaud, D, Pace-Asciak, C R, Livne, A A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8464865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.7.2589
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