Acute Versus Progressive Onset of Diabetes in NOD Mice: Potential Implications for Therapeutic Interventions in Type 1 Diabetes

Most natural history models for type 1 diabetes (T1D) propose that overt hyperglycemia results after a progressive loss of insulin-secreting β-cell mass and/or function. To experimentally address this concept, we prospectively determined morning blood glucose measurements every other day in multiple...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Mathews, Clayton E., Xue, Song, Posgai, Amanda, Lightfoot, Yaima L., Li, Xia, Lin, Andrea, Wasserfall, Clive, Haller, Michael J., Schatz, Desmond, Atkinson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613974/
https://ncbi.nlm.nih.gov/pubmed/26216853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0449
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