Role of µ, κ, and δ Opioid Receptors in Tibial Inhibition of Bladder Overactivity in Cats

In α-chloralose anesthetized cats, we examined the role of opioid receptor (OR) subtypes (µ, κ, and δ) in tibial nerve stimulation (TNS)-induced inhibition of bladder overactivity elicited by intravesical infusion of 0.25% acetic acid (AA). The sensitivity of TNS inhibition to cumulative i.v. doses...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Zhang, Zhaocun, Slater, Richard C., Ferroni, Matthew C., Kadow, Brian T., Lyon, Timothy D., Shen, Bing, Xiao, Zhiying, Wang, Jicheng, Kang, Audry, Roppolo, James R., de Groat, William C., Tai, Changfeng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613954/
https://ncbi.nlm.nih.gov/pubmed/26354994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.226845
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