Effect of Repeated Glucagon Doses on Hepatic Glycogen in Type 1 Diabetes: Implications for a Bihormonal Closed-Loop System

OBJECTIVE: To evaluate subjects with type 1 diabetes for hepatic glycogen depletion after repeated doses of glucagon, simulating delivery in a bihormonal closed-loop system. RESEARCH DESIGN AND METHODS: Eleven adult subjects with type 1 diabetes participated. Subjects underwent estimation of hepatic...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Castle, Jessica R., El Youssef, Joseph, Bakhtiani, Parkash A., Cai, Yu, Stobbe, Jade M., Branigan, Deborah, Ramsey, Katrina, Jacobs, Peter, Reddy, Ravi, Woods, Mark, Ward, W. Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Emerging Technologies and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613914/
https://ncbi.nlm.nih.gov/pubmed/26341131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc15-0754
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