Constitutively Active Acetylcholine-Dependent Potassium Current Increases Atrial Defibrillation Threshold by Favoring Post-Shock Re-Initiation

Electrical cardioversion (ECV), a mainstay in atrial fibrillation (AF) treatment, is unsuccessful in up to 10–20% of patients. An important aspect of the remodeling process caused by AF is the constitutive activition of the atrium-specific acetylcholine-dependent potassium current (I(K,ACh) → I(K,AC...

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Publicat a:Sci Rep
Autors principals: Bingen, Brian O., Askar, Saïd F. A., Neshati, Zeinab, Feola, Iolanda, Panfilov, Alexander V., de Vries, Antoine A. F., Pijnappels, Daniël A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613729/
https://ncbi.nlm.nih.gov/pubmed/26487066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15187
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