High homocysteine induces betaine depletion

Betaine is the substrate of the liver- and kidney-specific betaine-homocysteine (Hcy) methyltransferase (BHMT), an alternate pathway for Hcy remethylation. We hypothesized that BHMT is a major pathway for homocysteine removal in cases of hyperhomocysteinaemia (HHcy). Therefore, we measured betaine i...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Imbard, Apolline, Benoist, Jean-François, Esse, Ruben, Gupta, Sapna, Lebon, Sophie, de Vriese, An S, de Baulny, Helene Ogier, Kruger, Warren, Schiff, Manuel, Blom, Henk J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2015
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613678/
https://ncbi.nlm.nih.gov/pubmed/26182429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150094
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