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HMGA1-pseudogene overexpression contributes to cancer progression

Two pseudogenes for HMGA1, whose overexpression has a critical role in cancer progression, have been identified. They act as decoy for miRNAs that are able to target the HMGA1 gene then enhancing cell proliferation and migration. Moreover, these pseudogenes contain sequences that are potential targe...

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Publicat a:Cell Cycle
Autors principals: Esposito, Francesco, De Martino, Marco, Forzati, Floriana, Fusco, Alfredo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613653/
https://ncbi.nlm.nih.gov/pubmed/25483074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.974440
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