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LRRK2 dephosphorylation increases its ubiquitination
Activating mutations in the leucine rich repeat protein kinase 2 (LRRK2) gene are the most common cause of inherited Parkinson's disease (PD). LRRK2 is phosphorylated on a cluster of phosphosites including Ser(910), Ser(935), Ser(955) and Ser(973), which are dephosphorylated in several PD-relat...
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| Gepubliceerd in: | Biochem J |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Portland Press Ltd.
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613513/ https://ncbi.nlm.nih.gov/pubmed/25939886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141305 |
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