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Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis

Tourette syndrome is a heritable neurodevelopmental disorder whose pathophysiology remains unknown. Recent genome-wide association studies suggest that it is a polygenic disorder influenced by many genes of small effect. We tested whether these genes cluster in cellular function by applying gene-set...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: de Leeuw, Christiaan, Goudriaan, Andrea, Smit, August B, Yu, Dongmei, Mathews, Carol A, Scharf, Jeremiah M, Verheijen, Mark H G, Posthuma, Danielle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613465/
https://ncbi.nlm.nih.gov/pubmed/25735483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.22
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