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Rational Protein Engineering Guided by Deep Mutational Scanning

Sequence–function relationship in a protein is commonly determined by the three-dimensional protein structure followed by various biochemical experiments. However, with the explosive increase in the number of genome sequences, facilitated by recent advances in sequencing technology, the gap between...

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Pubblicato in:Int J Mol Sci
Autori principali: Shin, HyeonSeok, Cho, Byung-Kwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613353/
https://ncbi.nlm.nih.gov/pubmed/26404267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160923094
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