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Isolation of Specific Genomic Regions and Identification of Their Associated Molecules by Engineered DNA-Binding Molecule-Mediated Chromatin Immunoprecipitation (enChIP) Using the CRISPR System and TAL Proteins

Comprehensive understanding of genome functions requires identification of molecules (proteins, RNAs, genomic regions, etc.) bound to specific genomic regions of interest in vivo. To perform biochemical and molecular biological analysis of specific genomic regions, we developed engineered DNA-bindin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fujii, Hodaka, Fujita, Toshitsugu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613281/
https://ncbi.nlm.nih.gov/pubmed/26370991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160921802
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