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Role of RUNX2 in Breast Carcinogenesis

RUNX2 is a transcription factor playing the major role in osteogenesis, but it can be involved in DNA damage response, which is crucial for cancer transformation. RUNX2 can interact with cell cycle regulators: cyclin-dependent kinases, pRB and p21Cip1 proteins, as well as the master regulator of the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wysokinski, Daniel, Blasiak, Janusz, Pawlowska, Elzbieta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613236/
https://ncbi.nlm.nih.gov/pubmed/26404249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160920969
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