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Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.

Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay, using reduction of a tetrazolium salt as an indi...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Khurram, Muhammad, Lawton, Linda A., Edwards, Christine, Iriti, Marcello, Hameed, Abdul, Khan, Murad A., Khan, Farman A., ur Rahman, Shafiq
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613204/
https://ncbi.nlm.nih.gov/pubmed/26343638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160920290
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