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Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.

Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay, using reduction of a tetrazolium salt as an indi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Khurram, Muhammad, Lawton, Linda A., Edwards, Christine, Iriti, Marcello, Hameed, Abdul, Khan, Murad A., Khan, Farman A., ur Rahman, Shafiq
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613204/
https://ncbi.nlm.nih.gov/pubmed/26343638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160920290
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