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Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG(2) cells

Non-alcoholic fatty liver disease (NAFLD) is a prevalent liver disease associated with lipotoxicity, lipid peroxidation, oxidative stress, and inflammation. Nuciferine, an active ingredient extracted from the natural lotus leaf, has been reported to be effective for the prevention and treatment of N...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Dan-Dan, Zhang, Ji-Gang, Wu, Xin, Liu, Ying, Gu, Sheng-Ying, Zhu, Guan-Hua, Wang, Yu-Zhu, Liu, Gao-Lin, Li, Xiao-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612658/
https://ncbi.nlm.nih.gov/pubmed/26539118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00238
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