Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG(2) cells

Non-alcoholic fatty liver disease (NAFLD) is a prevalent liver disease associated with lipotoxicity, lipid peroxidation, oxidative stress, and inflammation. Nuciferine, an active ingredient extracted from the natural lotus leaf, has been reported to be effective for the prevention and treatment of N...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhang, Dan-Dan, Zhang, Ji-Gang, Wu, Xin, Liu, Ying, Gu, Sheng-Ying, Zhu, Guan-Hua, Wang, Yu-Zhu, Liu, Gao-Lin, Li, Xiao-Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612658/
https://ncbi.nlm.nih.gov/pubmed/26539118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00238
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