Prevalence of β(S)-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil

The aim of this study was to determine the frequency of beta S-globin gene (β(S) globin) haplotypes and alpha thalassemia with 3.7 kb deletion (−α(3.7kb) thalassemia) in the northwest region of Paraná state, and to investigate the oxidative and clinical-hematological profile of β(S) globin carriers...

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Bibliographic Details
Published in:Genet Mol Biol
Main Authors: Shimauti, Eliana LitsukoTomimatsu, Silva, Danilo Grunig Humberto, de Souza, Eniuce Menezes, de Almeida, Eduardo Alves, Leal, Francismar Prestes, Bonini-Domingos, Claudia Regina
Format: Artigo
Language:Inglês
Published: Sociedade Brasileira de Genética 2015
Subjects:
Human and Medical Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612597/
https://ncbi.nlm.nih.gov/pubmed/26500435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-475738320140231
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