Reconsidering the Role of Mitochondria in Aging

Background: Mitochondrial dysfunction has long been considered a major contributor to aging and age-related diseases. Harman’s Mitochondrial Free Radical Theory of Aging postulated that somatic mitochondrial DNA mutations that accumulate over the life span cause excessive production of reactive oxyg...

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Foilsithe in:J Gerontol A Biol Sci Med Sci
Main Authors: Gonzalez-Freire, Marta, de Cabo, Rafael, Bernier, Michel, Sollott, Steven J., Fabbri, Elisa, Navas, Placido, Ferrucci, Luigi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Review
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612387/
https://ncbi.nlm.nih.gov/pubmed/25995290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv070
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