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Co-mutation of p53, K-ras genes and accumulation of p53 protein and its correlation to clinicopathological features in rectal cancer

AIM: To determine the accuracy of p53 gene mutations predicted by overexpression of p53 protein immunohistochemically, and to investigate the co-mutation of p53 and K-ras genes in rectal cancer and its effect on promoting malignant biologic behaviors of tumors. METHODS: Ninety-seven specimens of rec...

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Detaylı Bibliyografya
Yayımlandı:World J Gastroenterol
Asıl Yazarlar: Pan, Zhi-Zhong, Wan, De-Sen, Chen, Gong, Li, Li-Ren, Lu, Zhen-Hai, Huang, Bi-Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Baishideng Publishing Group Inc 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612020/
https://ncbi.nlm.nih.gov/pubmed/15534934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i24.3688
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