Development of an oral DNA vaccine against MG7-Ag of gastric cancer using attenuated salmonella typhimurium as carrier

AIM: To develop an oral DNA vaccine against gastric cancer and evaluate its efficacy in mice. METHODS: The genes of the MG7-Ag mimotope and a universal Th epitope (Pan-DR epitope, PADRE) were included in the PCR primers. By PCR, the fusion gene of the two epitopes was amplified. The fusion gene was...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:World J Gastroenterol
Main Authors: Guo, Chang-Cun, Ding, Jie, Pan, Bo-Rong, Yu, Zhao-Cai, Han, Quan-Li, Meng, Fan-Ping, Liu, Na, Fan, Dai-Ming
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2003
Teme:
Gastric Cancer
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611782/
https://ncbi.nlm.nih.gov/pubmed/12800222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i6.1191
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