EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial–mesenchymal transition

Recent evidence indicates that long noncoding RNAs (lncRNAs) have a critical role in the regulation of cellular processes such as differentiation, proliferation, and metastasis. These lncRNAs are dysregulated in a variety of cancers and many function as tumor suppressors; however, the regulatory fac...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sun, M, Liu, X-H, Lu, K-H, Nie, F-Q, Xia, R, Kong, R, Yang, J-S, Xu, T-P, Liu, Y-W, Zou, Y-F, Lu, B-B, Yin, R, Zhang, E-B, Xu, L, De, W, Wang, Z-X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611729/
https://ncbi.nlm.nih.gov/pubmed/24967960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.256
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