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Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis

Chemotherapy resistance of tumor cells is a big challenge. Adaption to hypoxia is an essential cellular response that is controlled by the master oxygen-sensitive transcription factor HIF1 (hypoxia-inducible factor 1). The mechanism by which tumor cells acquire resistance to chemotherapy under hypox...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Zhang, D, Shi, Z, Li, M, Mi, J
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611715/
https://ncbi.nlm.nih.gov/pubmed/24967963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.240
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