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Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis
Chemotherapy resistance of tumor cells is a big challenge. Adaption to hypoxia is an essential cellular response that is controlled by the master oxygen-sensitive transcription factor HIF1 (hypoxia-inducible factor 1). The mechanism by which tumor cells acquire resistance to chemotherapy under hypox...
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| 發表在: | Cell Death Dis |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611715/ https://ncbi.nlm.nih.gov/pubmed/24967963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.240 |
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