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Dynamic ubiquitination drives herpesvirus neuroinvasion

Neuroinvasive herpesviruses display a remarkable propensity to enter the nervous system of healthy individuals in the absence of obvious trauma at the site of inoculation. We document a repurposing of cellular ubiquitin during infection to switch the virus between two invasive states. The states act...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Huffmaster, Nicholas J., Sollars, Patricia J., Richards, Alexsia L., Pickard, Gary E., Smith, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611658/
https://ncbi.nlm.nih.gov/pubmed/26407585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512559112
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