Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling

The contribution of endothelial-derived miR-17∼92 to ischemia-induced arteriogenesis has not been investigated in an in vivo model. In the present study, we demonstrate a critical role for the endothelial-derived miR-17∼92 cluster in shaping physiological and ischemia-triggered arteriogenesis. Endot...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Landskroner-Eiger, Shira, Qiu, Cong, Perrotta, Paola, Siragusa, Mauro, Lee, Monica Y., Ulrich, Victoria, Luciano, Amelia K., Zhuang, Zhen W., Corti, Federico, Simons, Michael, Montgomery, Rusty L., Wu, Dianqing, Yu, Jun, Sessa, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611600/
https://ncbi.nlm.nih.gov/pubmed/26417068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507094112
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