Contribution of eIF-4E inhibition to the expression and activity of heparanase in human colon adenocarcinoma cell line: LS-174T

AIM: Heparanase degrades heparan sulfate proteoglycans (HSPGs) and is a critical mediator of tumor metastasis and angiogenesis. Recently, it has been cloned as a single gene family and found to be a potential target for antimetastasis drugs. However, the molecular basis for the regulation of heparan...

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Enregistré dans:
Détails bibliographiques
Publié dans:World J Gastroenterol
Auteurs principaux: Yang, Yu-Jie, Zhang, Ya-Li, Li, Xu, Dan, Han-Lei, Lai, Zhuo-Sheng, Wang, Ji-De, Wang, Qun-Ying, Cui, Hai-Hong, Sun, Yong, Wang, Ya-Dong
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2003
Sujets:
Colorectal Cancer
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611528/
https://ncbi.nlm.nih.gov/pubmed/12918105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i8.1707
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