Codon 249 mutation in exon 7 of p53 gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China

AIM: One of the characteristics of hepatocellular carcinoma (HCC) in Qidong area is the selective mutation resulting in a serine substitution at codon 249 of the p53 gene (1, 20), and it has been identified as a “hotspot” mutation in heptocellular carcinomas occurring in populations exposed to aflat...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Huang, Xing-Hua, Sun, Lu-Hong, Lu, Dong-Dong, Sun, Yan, Ma, Li-Jie, Zhang, Xi-Ran, Huang, Jian, Yu, Long
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2003
Assuntos:
Liver Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611430/
https://ncbi.nlm.nih.gov/pubmed/12679912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i4.692
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