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Construction of a regulable gene therapy vector targeting for hepatocellular carcinoma

AIM: To construct a gene modified hepatocellular carcinoma (HCC) specific EGFP expression vector regulated by abbreviated cis-acting element of AFP gene. METHODS: The minimal essential DNA segments of AFP gene enhancer and promoter were synthesized through PCR from Genome DNA of HepG2 cells. Gene fr...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Lu, Shao-Ying, Sui, Yan-Fang, Li, Zeng-Shan, Pan, Cheng-En, Ye, Jing, Wang, Wen-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611429/
https://ncbi.nlm.nih.gov/pubmed/12679911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i4.688
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