Replication and gene expression of mutant hepatitis B virus in a transgenic mouse containing the complete viral genome with mutant s gene

AIM: To establish the transgenic mouse line harbouring complete hepatitis B virus (HBV) genome with mutant s gene (adr subtype). METHODS: Transgenic mice were generated by microinjecting HBV genome into fertilized eggs. Integration, expression, replication of HBV gene and histological changes in tra...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ge, Jun-Hui, Zhang, Le-Zhi, Li, Jian-Xiu, Liu, Hong, Liu, Hui-Min, He, Jin, Yao, Yu-Cheng, Yang, Yong-Ji, Yu, Hong-Yu, Hu, Yi-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Viral Hepatitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611258/
https://ncbi.nlm.nih.gov/pubmed/15457560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i21.3141
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