Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I

Stimulation of the antiviral response depends on the sensing of viral pathogen-associated molecular patterns (PAMPs) by specialized cellular proteins. During infection with RNA viruses, 5′-di- or -triphosphates accompanying specific single or double-stranded RNA motifs trigger signaling of intracell...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Xu, Jie, Mercado-López, Xiomara, Grier, Jennifer T., Kim, Won-keun, Chun, Lauren F., Irvine, Edward B., Del Toro Duany, Yoandris, Kell, Alison, Hur, Sun, Gale, Michael, Raj, Arjun, López, Carolina B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611036/
https://ncbi.nlm.nih.gov/pubmed/26443454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01265-15
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