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Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection

Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. In a large series of Malawian children hospitalized...

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Bibliografske podrobnosti
izdano v:mBio
Main Authors: Hochman, Sarah E., Madaline, Theresa F., Wassmer, Samuel C., Mbale, Emmie, Choi, Namjong, Seydel, Karl B., Whitten, Richard O., Varughese, Julie, Grau, Georges E. R., Kamiza, Steve, Molyneux, Malcolm E., Taylor, Terrie E., Lee, Sunhee, Milner, Danny A., Kim, Kami
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611030/
https://ncbi.nlm.nih.gov/pubmed/26396242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01390-15
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