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Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection

Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. In a large series of Malawian children hospitalized...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Hochman, Sarah E., Madaline, Theresa F., Wassmer, Samuel C., Mbale, Emmie, Choi, Namjong, Seydel, Karl B., Whitten, Richard O., Varughese, Julie, Grau, Georges E. R., Kamiza, Steve, Molyneux, Malcolm E., Taylor, Terrie E., Lee, Sunhee, Milner, Danny A., Kim, Kami
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611030/
https://ncbi.nlm.nih.gov/pubmed/26396242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01390-15
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