A human leucyl-tRNA synthetase as an anticancer target

Several aminoacyl-tRNA synthetases have been reported to be overexpressed for charging essential aminoacyl-tRNAs in many cancer types. In this study, we aimed to explore the potential role of leucyl-tRNA synthetase (LARS) as an anticancer target. MTT assay was performed to screen inhibitors to human...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Gao, Guangwei, Yao, Ying, Li, Kun, Mashausi, Dhahiri Saidi, Li, Dongsheng, Negi, Hema, Kamle, Suchitra, Chen, Hao, Wu, Zhenghua, Zhou, Huchen, Li, Dawei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610879/
https://ncbi.nlm.nih.gov/pubmed/26508878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S88873
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