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A vaccine formulated with the major outer membrane protein can protect C3H/HeN, a highly susceptible strain of mice, from a Chlamydia muridarum genital challenge

C3H/HeN female mice were vaccinated with native Chlamydia muridarum major outer membrane protein (MOMP), using Montanide+CpG or Alum+CpG as adjuvants. Negative control groups were immunized with ovalbumin (OVA) and the same adjuvants. As positive control, mice were inoculated intranasally with live...

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Détails bibliographiques
Publié dans:Immunology
Auteurs principaux: Pal, Sukumar, Tatarenkova, Olga V, de la Maza, Luis M
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610632/
https://ncbi.nlm.nih.gov/pubmed/26423798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12520
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