Repeated exposure to low doses of kainic acid activates Nuclear Factor Kappa B (NF-κB) prior to seizure in transgenic NF-κB/EGFP reporter mice

Predicting seizurogenic properties of pharmacologically active compounds is difficult due to the complex nature of the mechanisms involved and because of the low sensitivity and high variability associated with current behavioral-based methods. To identify early neuronal signaling events predictive...

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Publicado no:Neurotoxicology
Main Authors: Miller, James A., Kirkley, Kelly A., Padmanabhan, Rachel, Liang, Li-Ping, Raol, Yogendra H., Patel, Manisha, Bialecki, Russell A., Tjalkens, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610362/
https://ncbi.nlm.nih.gov/pubmed/24813937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2014.04.010
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