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Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological Evaluation
[Image: see text] Protein arginine methyltransferase 1 (PRMT1) is involved in many biological activities, such as gene transcription, signal transduction, and RNA processing. Overexpression of PRMT1 is related to cardiovascular diseases, kidney diseases, and cancers; therefore, selective PRMT1 inhib...
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| Опубликовано в: : | J Med Chem |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American
Chemical
Society
2015
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610307/ https://ncbi.nlm.nih.gov/pubmed/25559100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501452j |
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