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Tamoxifen Augments the Innate Immune Function of Neutrophils Through Modulation of Intracellular Ceramide

Tamoxifen is a selective estrogen receptor modulator widely used for the treatment of breast cancer. In addition to its activity as an estrogen receptor agonist/antagonist, tamoxifen also modulates sphingolipid biosynthesis, which has been shown to play an important role in the regulation of neutrop...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Corriden, Ross, Hollands, Andrew, Olson, Joshua, Derieux, Jaclyn, Lopez, Justine, Chang, John T., Gonzalez, David J., Nizet, Victor
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610010/
https://ncbi.nlm.nih.gov/pubmed/26458291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9369
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