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Identification of TGF-β receptor-1 as a key regulator of carbon nanotube-induced fibrogenesis

Carbon nanotubes (CNTs) induce rapid interstitial lung fibrosis, but the underlying mechanisms are unclear. Previous studies indicated that the ability of CNTs to penetrate lung epithelium, enter interstitial tissue, and stimulate fibroblasts to produce collagen matrix is important to lung fibrosis....

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Mishra, Anurag, Stueckle, Todd A., Mercer, Robert R., Derk, Raymond, Rojanasakul, Yon, Castranova, Vincent, Wang, Liying
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609943/
https://ncbi.nlm.nih.gov/pubmed/26472812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00002.2015
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