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Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure
The helicase Twinkle is indispensable for mtDNA replication in nucleoids. Previously, we showed that Twinkle is tightly membrane-associated even in the absence of mtDNA, which suggests that Twinkle is part of a membrane-attached replication platform. Here we show that this platform is a cholesterol-...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609938/ https://ncbi.nlm.nih.gov/pubmed/26478270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15292 |
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