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A novel mutation of AFG3L2 might cause dominant optic atrophy in patients with mild intellectual disability

Dominant optic neuropathies causing fiber loss in the optic nerve are among the most frequent inherited mitochondrial diseases. In most genetically resolved cases, the disease is associated to a mutation in OPA1, which encodes an inner mitochondrial dynamin involved in network fusion, cristae struct...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Genet
Egile Nagusiak: Charif, Majida, Roubertie, Agathe, Salime, Sara, Mamouni, Sonia, Goizet, Cyril, Hamel, Christian P., Lenaers, Guy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609881/
https://ncbi.nlm.nih.gov/pubmed/26539208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00311
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