Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually

Influenza is a vaccine-preventable contagious respiratory illness caused by influenza (flu) viruses which can lead to hospitalization and sometimes even death. Current flu vaccines delivered intramuscularly (IM) or intradermally (ID) are less effective at eliciting protective mucosal immune response...

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Veröffentlicht in:Vaccine
Hauptverfasser: Spinner, Justin L., Oberoi, Hardeep S., Yorgensen, Yvonne M., Poirier, Danielle S., Burkhart, David J., Plante, Martin, Evans, Jay T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609623/
https://ncbi.nlm.nih.gov/pubmed/26392012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.08.086
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