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Improvement of tuberous sclerosis complex skin tumors during long-term treatment with oral sirolimus

BACKGROUND: Oral mechanistic target of rapamycin (mTOR) inhibitors have been shown to reduce visceral tumor volume in tuberous sclerosis complex (TSC) patients. OBJECTIVE: To evaluate the cutaneous response to oral sirolimus in TSC patients with an indication for systemic treatment, including long-t...

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Detalhes bibliográficos
Publicado no:J Am Acad Dermatol
Main Authors: Nathan, Neera, Wang, Ji-an, Li, Shaowei, Cowen, Edward W., Haughey, Mary, Moss, Joel, Darling, Thomas N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609596/
https://ncbi.nlm.nih.gov/pubmed/26365597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaad.2015.07.018
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