The Expansion of CD25(high)IL-10(high)FoxP3(high) B Regulatory Cells Is in Association with SLE Disease Activity

B regulatory cells (Bregs) belong to a subgroup of activated B cells tasked with maintaining self-tolerance and preventing autoimmunity. While sharing similar regulatory mechanisms such as IL-10 dependency, they also defer in exhibiting their suppressive effects by expressing Fas-Ligand, TGF-beta, a...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Vadasz, Zahava, Peri, Regina, Eiza, Nasren, Slobodin, Gleb, Balbir-Gurman, Alexandra, Toubi, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609458/
https://ncbi.nlm.nih.gov/pubmed/26504851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/254245
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