Exome sequencing reveals AMER1 as a frequently mutated gene in colorectal cancer

PURPOSE: Somatic mutations occur at early stages of adenoma and accumulate throughout colorectal cancer (CRC) progression. The aim of this study was to characterize the mutational landscape of stage II tumors and to search for novel recurrent mutations likely implicated in CRC tumorigenesis. DESIGN:...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Sanz-Pamplona, Rebeca, Lopez-Doriga, Adriana, Paré-Brunet, Laia, Lázaro, Kira, Bellido, Fernando, Alonso, M. Henar, Aussó, Susanna, Guinó, Elisabet, Beltrán, Sergi, Castro-Giner, Francesc, Gut, Marta, Sanjuan, Xavier, Closa, Adria, Cordero, David, Morón-Duran, Francisco D., Soriano, Antonio, Salazar, Ramón, Valle, Laura, Moreno, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609254/
https://ncbi.nlm.nih.gov/pubmed/26071483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0159
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