Mevalonate Pathway Antagonist Inhibits Proliferation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models

PURPOSE: Statins are among the most frequently prescribed drugs because of their efficacy and low toxicity in treating hypercholesterolemia. Recently, statins have been reported to inhibit the proliferative activity of cancer cells, especially those with TP53 mutations. Since TP53 mutations occur in...

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Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Kobayashi, Yusuke, Kashima, Hiroyasu, Wu, Ren-Chin, Jung, Jin- Gyoung, Kuan, Jen-Chun, Gu, Jinghua, Xuan, Jianhua, Sokoll, Lori, Visvanathan, Kala, Shih, Ie-Ming, Wang, Tian-Li
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609247/
https://ncbi.nlm.nih.gov/pubmed/26109099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3368
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